A bathroom's footprint depends on its fixtures, clearances, door swing, and whether it is a half bath, full bath, or primary bath. U.S. builders' survey data gives a useful new-home comparison, while sample floor plans show how compact layouts can work. Neither is a universal building standard.
For context, NAHB's November 2018 survey of 153 single-family builders reported an average 165 square feet allocated to the master bathroom across all surveyed homes. For non-master bathrooms, the allocated average was 166 square feet across all homes. These figures reflect builders' estimates in typical new homes averaging 2,913 square feet—not a target for a single small guest bathroom.